Tfcp2l1^{Gt(pLSABetageo)1Sjt}
Gene trapped Allele Detail

Summary

• Symbol: Tfcp2l1^{Gt(pLSABetageo)1Sjt}
• Name: transcription factor CP2-like 1; gene trap 1, Shinji Takada
• MGI ID: MGI:3707684
• Synonyms: Cp2l1^tra
• Gene: Tfcp2l1 Location: Chr1:118555675-118612898 bp, + strand Genetic Position: Chr1, 52.14 cM, cytoband E2
• Alliance: Tfcp2l1^{Gt(pLSABetageo)1Sjt} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:98395
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The pLSABetageo vector was modified from the SA-IRESBetageo vector by the addition of lox71 sequences upstream of the splice acceptor site. The vector was inserted in the second intron. 5' RACE demonastrated that a fusion transcript was generated by the splicing of exon 2 with the engrailed-2 splicing acceptor and betageo. (J:98395)

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tfcp2l1 Mutation: 99 strains or lines available

References

• Original: J:98395 Yamaguchi Y, et al., Gene trap screening as an effective approach for identification of Wnt-responsive genes in the mouse embryo. Dev Dyn. 2005 Jun;233(2):484-95
• All: 2 reference(s)