Tcrbtm3Che
Targeted Allele Detail
|
|
| Symbol: |
Tcrbtm3Che |
| Name: |
T cell receptor beta chain; targeted mutation 3, Jianzhu Chen |
| MGI ID: |
MGI:3708170 |
| Synonyms: |
Vbeta(neo) |
| Gene: |
Tcrb Location: Chr6:40868230-41535305 bp, + strand Genetic Position: Chr6, cytoband A-C
|
|
| Germline Transmission: |
Earliest citation of germline transmission:
J:120387
|
| Parent Cell Line: |
J1 (ES Cell)
|
| Strain of Origin: |
129S4/SvJae
|
|
| Allele Type: |
|
Targeted |
| Mutation: |
|
Insertion
|
| |
|
Mutation details: The Vbeta13 gene segment with its endogenous promoter and recombination signal sequences and a floxed pgk-neomycin resistance cassette is inserted upstream of the D segment. Insertion was confirmed by Southern blot analysis of ES cells and by increased expression of Vbeta13 T cells in homozygous mice.
(J:120387)
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
| Carrying any Tcrb Mutation: |
97 strains or lines available
|
|
| Original: |
J:120387 Sieh P, et al., Distinct control of the frequency and allelic exclusion of the V beta gene rearrangement at the TCR beta locus. J Immunol. 2001 Aug 15;167(4):2121-9 |
| All: |
1 reference(s) |
|
Analysis Tools
