Usp53^mbo
Chemically induced Allele Detail

Summary

• Symbol: Usp53^mbo
• Name: ubiquitin specific peptidase 53; mambo
• MGI ID: MGI:3708452
• Gene: Usp53 Location: Chr3:122725142-122778159 bp, - strand Genetic Position: Chr3, 53.75 cM, cytoband G3
• Alliance: Usp53^mbo page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU) (Null/knockout)
• Mutation: Single point mutation
• Mutation details: This phenotypic mutant was identified in an ENU mutagenesis screen. The molecular lesion is a T-to-A transversion (c.682T>A) located in coding exon 7 of the gene (p.C228S), which encodes part of the USP catalytic domain. (J:227841)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Usp53 Mutation: 75 strains or lines available

References

• Original: J:119820 Schwander M, et al., A forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell function. J Neurosci. 2007 Feb 28;27(9):2163-75
• All: 2 reference(s)