Sebox^tm1Clc
Targeted Allele Detail

Summary

• Symbol: Sebox^tm1Clc
• Name: SEBOX homeobox; targeted mutation 1, Constance L Cepko
• MGI ID: MGI:3708903
• Gene: Sebox Location: Chr11:78394328-78395907 bp, + strand Genetic Position: Chr11, 46.74 cM
• Alliance: Sebox^tm1Clc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:120986
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A targeting vector was used to flank the entire gene with loxP sites and insert a Frt-flanked PGK-neomycin resistance cassette in reverse orientation. The gene was deleted by crossing these mice to a germline Cre strain, and subsequently mated to a line of germline Flp recombinase expressing mice, leaving a single loxP and an Frt site. No gene expression is detected by RNA-ISH. (J:120986)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sebox Mutation: 10 strains or lines available

References

• Original: J:120986 Cepko CL, Generation of a Knockout Allele of Og9x. MGI Direct Data Submission. 2007
• All: 1 reference(s)