Tg(Npy-hrGFP)1Lowl
Transgene Detail

Summary

• Symbol: Tg(Npy-hrGFP)1Lowl
• Name: transgene insertion 1, Bradford B Lowell
• MGI ID: MGI:3709190
• Synonyms: NPY-GFP, Npy-hrGFP
• Transgene: Tg(Npy-hrGFP)1Lowl Location: unknown
• Alliance: Tg(Npy-hrGFP)1Lowl page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: A bacterial artificial chromosome (BAC) was modified by inserting a humanized Renilla GFP (hrGFP, Stratagene) sequence into the translational start site of the mouse neuropeptide Y (Npy) gene. Correctly transformed and targeted bacteria were used to isolate the ~200 kb transgenic construct (called "NPY-GFP"). This NPY-GFP transgene was used for pronuclear injection into fertilized one-cell stage FVB embryos. Founder line 1 showing germline transmission was established. Brain tissues show GFP fluorescence when exposed to UV light. (J:120993)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:120993 Lowell BB, Generation of transgenic reporter mice with umanized Renilla GFP under control of the NPY promoter. MGI Direct Data Submission. 2007
• All: 153 reference(s)