Tg(Scgb1a1-GH1)4-5Gtn
Transgene Detail

Summary

• Symbol: Tg(Scgb1a1-GH1)4-5Gtn
• Name: transgene insertion 4-5, Jonathan D Gitlin
• MGI ID: MGI:3709263
• Transgene: Tg(Scgb1a1-GH1)4-5Gtn Location: unknown
• Alliance: Tg(Scgb1a1-GH1)4-5Gtn page

Small size and delayed hair appearance in 2 week old Tg(Scgb1a1-GH1)4-5Gtn/0 mice

Show the 1 phenotype image(s) involving this allele.

Transgene origin

• Strain of Origin: (C57BL/6 x SJL)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Scgb1a1-GH1)4-5Gtn expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  GH1 (2688)

  Gh	(MGI:95707)

• Mutation details: This transgene consists of 2.3 Kb of the rat Scgb1a1 5' flanking region and the human growth hormone gene. Scgb1a1 drives the expression of GH1 in Clara cells in the bronchiolar epithelium. (J:101823)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:101823 Hackett BP, et al., Cell-specific expression of a Clara cell secretory protein-human growth hormone gene in the bronchiolar epithelium of transgenic mice. Proc Natl Acad Sci U S A. 1992 Oct 1;89(19):9079-83
• All: 1 reference(s)