Plxdc1^tm1Matl
Targeted Allele Detail

Summary

• Symbol: Plxdc1^tm1Matl
• Name: plexin domain containing 1; targeted mutation 1, Marc Tessier-Lavigne
• MGI ID: MGI:3709571
• Synonyms: Plxdc1-Betageo
• Gene: Plxdc1 Location: Chr11:97814064-97877270 bp, - strand Genetic Position: Chr11, 61.31 cM
• Alliance: Plxdc1^tm1Matl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:121225
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A targeted trap vector was fused to gene-specific homology arms such that homologous recombination was used to insert the vector into intron 11 of the locus. This vector contains a splice acceptor, betagalactosidase, IRES-PLAP and polyA signal. (J:121225)

Expression

In Mice Carrying this Mutation:

7 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Plxdc1 Mutation: 32 strains or lines available

References

• Original: J:121225 Friedel RH, et al., Gene targeting using a promoterless gene trap vector ('targeted trapping') is an efficient method to mutate a large fraction of genes. Proc Natl Acad Sci U S A. 2005 Sep 13;102(37):13188-93
• All: 2 reference(s)