About   Help   FAQ
Gt(ROSA)26Sortm1(Mirn155)Rsky
Targeted Allele Detail
Summary
Symbol: Gt(ROSA)26Sortm1(Mirn155)Rsky
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Klaus Rajewsky
MGI ID: MGI:3709879
Synonyms: B-cellmir155, Gt(ROSA)26Sortm1(Mir155)Rsky
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sortm1(Mirn155)Rsky page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:121084
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, Inserted expressed sequence, Reporter)
Mutation:    Insertion
 
Gt(ROSA)26Sortm1(Mirn155)Rsky expresses 1 gene
 
Mutation detailsA vector containing the CAG promoter, a floxed neo and transcriptional STOP cassette, and microRNA 155 cDNA was inserted into the locus. An frt-flanked IRES-EGFP and polyA signal were placed downstream of the microRNA 155 cDNA. (J:121084)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  992 strains or lines available
References
Original:  J:121084 Thai TH, et al., Regulation of the germinal center response by microRNA-155. Science. 2007 Apr 27;316(5824):604-8
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
10/29/2024
MGI 6.24
The Jackson Laboratory