Atn1^tm1.1Asp
Targeted Allele Detail

Summary

• Symbol: Atn1^tm1.1Asp
• Name: atrophin 1; targeted mutation 1.1, Andrew S Peterson
• MGI ID: MGI:3709882
• Synonyms: Atn1delta
• Gene: Atn1 Location: Chr6:124719507-124733450 bp, - strand Genetic Position: Chr6, 59.17 cM
• Alliance: Atn1^tm1.1Asp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:120958
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exons 2-7, containing the initiator codon and 90% of the coding region, were removed via transient cre expression in ES cells. Northern blot confirmed absence of wild-type transcript. (J:120958)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atn1 Mutation: 49 strains or lines available

References

• Original: J:120958 Shen Y, et al., Functional architecture of atrophins. J Biol Chem. 2007 Feb 16;282(7):5037-44
• All: 2 reference(s)