Ptprrtm1Wjh
Targeted Allele Detail
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Symbol: |
Ptprrtm1Wjh |
Name: |
protein tyrosine phosphatase receptor type R; targeted mutation 1, Wiljan J A J Hendriks |
MGI ID: |
MGI:3710117 |
Synonyms: |
Ptprr- |
Gene: |
Ptprr Location: Chr10:115854118-116110837 bp, + strand Genetic Position: Chr10, 64.01 cM, cytoband A2
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Alliance: |
Ptprrtm1Wjh page
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Germline Transmission: |
Earliest citation of germline transmission:
J:121302
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Exon 6 was replaced by a neomycin resistance cassette. With the gene having 3 transcription start sites, loss of exon 6 would shift the reading frame in any residual transcript. Northern blot, immunoprecipitation and immunoblot confirmed absence of all isoforms in mutants.
(J:121302)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Ptprr Mutation: |
38 strains or lines available
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Original: |
J:121302 Chirivi RG, et al., Altered MAP kinase phosphorylation and impaired motor coordination in PTPRR deficient mice. J Neurochem. 2007 May;101(3):829-40 |
All: |
2 reference(s) |
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