Lbx1^{tm3.1(cre)Cbm}
Targeted Allele Detail

Summary

• Symbol: Lbx1^{tm3.1(cre)Cbm}
• Name: ladybird homeobox 1; targeted mutation 3.1, Carmen Birchmeier
• MGI ID: MGI:3710149
• Synonyms: Lbx1^Cre
• Gene: Lbx1 Location: Chr19:45221123-45224251 bp, - strand Genetic Position: Chr19, 38.61 cM, cytoband D
• Alliance: Lbx1^{tm3.1(cre)Cbm} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:121332
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutations: Insertion, Intragenic deletion
• Lbx1^{tm3.1(cre)Cbm} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Lbx1 (MGI:104867)

• Mutation details: A cre cDNA and a floxed neomycin cassette replaced exon 1. The neo was removed by FLP mediated recombination in the germline. (J:121332)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Lbx1 (mouse) Summary of all recombinase alleles driven by Lbx1. Alliance mouse Lbx1 gene page

Expression

In Mice Carrying this Mutation:

8 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lbx1 Mutation: 13 strains or lines available

References

• Original: J:121332 Sieber MA, et al., Lbx1 acts as a selector gene in the fate determination of somatosensory and viscerosensory relay neurons in the hindbrain. J Neurosci. 2007 May 2;27(18):4902-9
• All: 23 reference(s)