Ift88^tm1.1Bky
Targeted Allele Detail

Summary

• Symbol: Ift88^tm1.1Bky
• Name: intraflagellar transport 88; targeted mutation 1.1, Bradley K Yoder
• MGI ID: MGI:3710186
• Synonyms: Ift88ⁿ, Ift88^null
• Gene: Ift88 Location: Chr14:57661519-57755393 bp, + strand Genetic Position: Chr14, 30.1 cM
• Alliance: Ift88^tm1.1Bky page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:117033
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 4-6 were removed via cre mediated recombination in the germline, resulting in a translational frame shift and loss of all protein function. (J:117033)

Expression

In Mice Carrying this Mutation:	2 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	15 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ift88 Mutation: 48 strains or lines available

References

• Original: J:117033 Haycraft CJ, et al., Intraflagellar transport is essential for endochondral bone formation. Development. 2007 Jan;134(2):307-16
• All: 14 reference(s)