Slc16a2^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Slc16a2^tm1Dgen
• Name: solute carrier family 16 (monocarboxylic acid transporters), member 2; targeted mutation 1, Deltagen
• MGI ID: MGI:3710233
• Synonyms: Mct8^-
• Gene: Slc16a2 Location: ChrX:102741020-102865589 bp, - strand Genetic Position: ChrX, 46.29 cM
• Alliance: Slc16a2^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:120737
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 33 bp-fragment of exon 2 was replaced with a lacZ-neo cassette. Absence of protein was confirmed by Western blot of mutant liver homogenates. (J:120737)

Disease models

Expression

In Mice Carrying this Mutation:	8 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc16a2 Mutation: 9 strains or lines available

References

• Original: J:120737 Trajkovic M, et al., Abnormal thyroid hormone metabolism in mice lacking the monocarboxylate transporter 8. J Clin Invest. 2007 Mar;117(3):627-35
• All: 20 reference(s)