Slc2a3^tm1Dksr
Targeted Allele Detail

Summary

• Symbol: Slc2a3^tm1Dksr
• Name: solute carrier family 2 (facilitated glucose transporter), member 3; targeted mutation 1, Sherin U Devaskar
• MGI ID: MGI:3710246
• Synonyms: Glut3^-
• Gene: Slc2a3 Location: Chr6:122704768-122778599 bp, - strand Genetic Position: Chr6, 57.82 cM
• Alliance: Slc2a3^tm1Dksr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:121238
• Parent Cell Line: LW1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A targeting vector was designed to replace exons 7-9 and the coding region of exon 10 with a neomycin resistance gene. (J:121238)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc2a3 Mutation: 43 strains or lines available

References

• Original: J:121238 Ganguly A, et al., Glucose transporter isoform-3 mutations cause early pregnancy loss and fetal growth restriction. Am J Physiol Endocrinol Metab. 2007 May;292(5):E1241-55
• All: 4 reference(s)