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Taf7ltm1.1Jw
Targeted Allele Detail
Summary
Symbol: Taf7ltm1.1Jw
Name: TATA-box binding protein associated factor 7 like; targeted mutation 1.1, Jeremy Wang
MGI ID: MGI:3710399
Synonyms: Taf7l-
Gene: Taf7l  Location: ChrX:133360867-133377239 bp, - strand  Genetic Position: ChrX, 56.18 cM
Alliance: Taf7ltm1.1Jw page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:121371
Parent Cell Line:  v6.5 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsExons 2 through 6 are removed by cre-mediated recombination to yield a null allele. The absence of protein product was confirmed by western blot analysis of testis protein extracts. (J:121371)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 17 assay results
3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 7 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Taf7l Mutation:  2 strains or lines available
References
Original:  J:121371 Cheng Y, et al., Abnormal sperm in mice lacking the Taf7l gene. Mol Cell Biol. 2007 Apr;27(7):2582-9
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory