Tg(Myh6-Ccnd1)#Ljf
Transgene Detail

Summary

• Symbol: Tg(Myh6-Ccnd1)#Ljf
• Name: transgene insertion #, Loren J Field
• MGI ID: MGI:3710407
• Synonyms: MHC-CYCD1
• Transgene: Tg(Myh6-Ccnd1)#Ljf Location: unknown
• Alliance: Tg(Myh6-Ccnd1)#Ljf page

Transgene origin

• Strain of Origin: C3HeB/FeJ

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Myh6-Ccnd1)#Ljf expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Ccnd1 (MGI:88313)

• Mutation details: This transgene consists of the mouse alpha-cardiac myosin heavy chain promoter and the mouse cyclin D1 gene. Western blot confirmed expression of Ccnd1 specifically in the heart. Three lines (7, 12, and 21) were made and data is pooled from the lines. (J:40920)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:40920 Soonpaa MH, et al., Cyclin D1 overexpression promotes cardiomyocyte DNA synthesis and multinucleation in transgenic mice. J Clin Invest. 1997 Jun 1;99(11):2644-54
• All: 3 reference(s)