Onecut3^tm1Jqmn
Targeted Allele Detail

Summary

• Symbol: Onecut3^tm1Jqmn
• Name: one cut domain, family member 3; targeted mutation 1, Patrick Jacquemin
• MGI ID: MGI:3711023
• Synonyms: oc3^-
• Gene: Onecut3 Location: Chr10:80330740-80353100 bp, + strand Genetic Position: Chr10, 39.72 cM
• Alliance: Onecut3^tm1Jqmn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:121610
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Exon 1 was replaced by a GFP-PGK-neo cassette, resulting in a null allele. (J:121610)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Onecut3 Mutation: 14 strains or lines available

References

• Original: J:121610 Vanhorenbeeck V, et al., Role of the Onecut transcription factors in pancreas morphogenesis and in pancreatic and enteric endocrine differentiation. Dev Biol. 2007 May 15;305(2):685-94
• All: 2 reference(s)