Bmper^tm1Emdr
Targeted Allele Detail

Summary

• Symbol: Bmper^tm1Emdr
• Name: BMP-binding endothelial regulator; targeted mutation 1, E M de Robertis
• MGI ID: MGI:3711028
• Synonyms: CV-2, CV2
• Gene: Bmper Location: Chr9:23134372-23396496 bp, + strand Genetic Position: Chr9, 9.55 cM, cytoband A4
• Alliance: Bmper^tm1Emdr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:121684
• Parent Cell Line: LW1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A targeting vector was used to place an in-frame LacZ reporter gene in the first exon of the gene at the initiator methionine deleting exon 2 and insert a neomycin resistance cassette downstream of LacZ. (J:121684, J:141243)

Expression

In Mice Carrying this Mutation:	29 assay results
In Structures Affected by this Mutation:	15 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Bmper Mutation: 47 strains or lines available

References

• Original: J:121684 de Robertis EM, A targeted mutation of Bmper. MGI Direct Data Submission. 2007
• All: 8 reference(s)