Foxp1^tm1Rao
Targeted Allele Detail

Summary

• Symbol: Foxp1^tm1Rao
• Name: forkhead box P1; targeted mutation 1, Anjana Rao
• MGI ID: MGI:3711150
• Synonyms: Foxp^-
• Gene: Foxp1 Location: Chr6:98902299-99499682 bp, - strand Genetic Position: Chr6, 45.74 cM, cytoband E1
• Alliance: Foxp1^tm1Rao page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:112644
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A lacZ-neo was inserted to replace the sequence encoding the N-terminal two thirds of the protein, including the entire forkhead domain. The construct also removed the first translation start site to ensure efficient translation from the lacZ start codon. (J:112644)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Foxp1 Mutation: 77 strains or lines available

References

• Original: J:112644 Hu H, et al., Foxp1 is an essential transcriptional regulator of B cell development. Nat Immunol. 2006 Aug;7(8):819-26
• All: 2 reference(s)