Zbtb7a^tm1Ppp
Targeted Allele Detail

Summary

• Symbol: Zbtb7a^tm1Ppp
• Name: zinc finger and BTB domain containing 7a; targeted mutation 1, Pier Paolo Pandolfi
• MGI ID: MGI:3711162
• Synonyms: Zbtb7a^-
• Gene: Zbtb7a Location: Chr10:80971113-80988056 bp, + strand Genetic Position: Chr10, 39.72 cM, cytoband B5.3
• Alliance: Zbtb7a^tm1Ppp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:121576
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Transient cre expression was used to remove most of exon 2 and a floxed neo that had been inserted into the locus. A GFP cassette remained in frame, however, fluorescence was not detected. (J:121576)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zbtb7a Mutation: 64 strains or lines available

References

• Original: J:121576 Maeda T, et al., Regulation of B versus T lymphoid lineage fate decision by the proto-oncogene LRF. Science. 2007 May 11;316(5826):860-6
• All: 6 reference(s)