Nol3^tm1Rvh
Targeted Allele Detail

Summary

• Symbol: Nol3^tm1Rvh
• Name: nucleolar protein 3 (apoptosis repressor with CARD domain); targeted mutation 1, Rudiger von Harsdorf
• MGI ID: MGI:3711185
• Synonyms: Arc^-
• Gene: Nol3 Location: Chr8:106002777-106008571 bp, + strand Genetic Position: Chr8, 53.04 cM, cytoband D1
• Alliance: Nol3^tm1Rvh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:121501
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 2, 3 and 4 were replaced with a neomycin resistance cassette. (J:121501)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nol3 Mutation: 9 strains or lines available

References

• Original: J:121501 Donath S, et al., Apoptosis repressor with caspase recruitment domain is required for cardioprotection in response to biomechanical and ischemic stress. Circulation. 2006 Mar 7;113(9):1203-12
• All: 4 reference(s)