Pygo2^tm1.1Ssp
Targeted Allele Detail

Summary

• Symbol: Pygo2^tm1.1Ssp
• Name: pygopus 2; targeted mutation 1, S Steven Potter
• MGI ID: MGI:3711233
• Synonyms: Pygo2^flox, Pygo2^tm1Lan
• Gene: Pygo2 Location: Chr3:89337521-89342435 bp, + strand Genetic Position: Chr3, 39.12 cM
• Alliance: Pygo2^tm1.1Ssp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:121416
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• LoxP sites were inserted to flank exon 3. (J:121416)

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pygo2 Mutation: 24 strains or lines available

References

• Original: J:121416 Song N, et al., pygopus 2 has a crucial, Wnt pathway-independent function in lens induction. Development. 2007 May;134(10):1873-85
• All: 1 reference(s)