Prpf19^tm1Glri
Targeted Allele Detail

Summary

• Symbol: Prpf19^tm1Glri
• Name: pre-mRNA processing factor 19; targeted mutation 1, Johannes Grillari
• MGI ID: MGI:3711357
• Synonyms: Snev^-
• Gene: Prpf19 Location: Chr19:10872595-10886923 bp, + strand Genetic Position: Chr19, 7.33 cM
• Alliance: Prpf19^tm1Glri page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:121379
• Parent Cell Line: HM-1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd-Hprt1^b-m3

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 1-6 were replaced by a lacZ reporter and a neomycin resistance cassette, both containing polyA signals and the latter also carrying a Rous sarcoma virus promoter. (J:121379)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prpf19 Mutation: 19 strains or lines available

References

• Original: J:121379 Fortschegger K, et al., Early embryonic lethality of mice lacking the essential protein SNEV. Mol Cell Biol. 2007 Apr;27(8):3123-30
• All: 2 reference(s)