Pcyt2^tm1Mbak
Targeted Allele Detail

Summary

• Symbol: Pcyt2^tm1Mbak
• Name: phosphate cytidylyltransferase 2, ethanolamine; targeted mutation 1, Marica Bakovic
• MGI ID: MGI:3711450
• Synonyms: Pyct2^-
• Gene: Pcyt2 Location: Chr11:120500913-120508762 bp, - strand Genetic Position: Chr11, 84.33 cM, cytoband E2
• Alliance: Pcyt2^tm1Mbak page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:121387
• Parent Cell Line: iTL1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 1-3 were replaced with a neomycin resistance gene. (J:121387)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pcyt2 Mutation: 26 strains or lines available

References

• Original: J:121387 Fullerton MD, et al., Developmental and metabolic effects of disruption of the mouse CTP:phosphoethanolamine cytidylyltransferase gene (Pcyt2). Mol Cell Biol. 2007 May;27(9):3327-36
• All: 5 reference(s)