Maf^ENU424
Chemically induced Allele Detail

Summary

• Symbol: Maf^ENU424
• Name: MAF bZIP transcription factor; ENU424
• MGI ID: MGI:3711715
• Gene: Maf Location: Chr8:116429992-116433633 bp, - strand Genetic Position: Chr8, 62.61 cM
• Alliance: Maf^ENU424 page

Mutation origin

• Strain of Origin: (C3H/El x 102/El)F1

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: An A to T transversion at position 269 resulted in an aspartic acid to valine substitution at amino acid position 90 (D90V) in the N-terminal transactivation domain. (J:121758)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Maf Mutation: 27 strains or lines available

References

• Original: J:121758 Perveen R, et al., A heterozygous c-Maf transactivation domain mutation causes congenital cataract and enhances target gene activation. Hum Mol Genet. 2007 May 1;16(9):1030-8
• All: 1 reference(s)