Mpp4^tm1Tili
Targeted Allele Detail

Summary

• Symbol: Mpp4^tm1Tili
• Name: membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4); targeted mutation 1, Tiansen Li
• MGI ID: MGI:3711731
• Synonyms: Mpp4^-
• Gene: Mpp4 Location: Chr1:59160094-59202548 bp, - strand Genetic Position: Chr1, 29.2 cM
• Alliance: Mpp4^tm1Tili page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:121771
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2, which contains the translational start codon, was replaced with a neomycin resistance cassette. Immunoblot confirmed absence of protein in mutants. (J:121771)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mpp4 Mutation: 42 strains or lines available

References

• Original: J:121771 Yang J, et al., Mpp4 is required for proper localization of plasma membrane calcium ATPases and maintenance of calcium homeostasis at the rod photoreceptor synaptic terminals. Hum Mol Genet. 2007 May 1;16(9):1017-29
• All: 1 reference(s)