Tsc2^tm1.2Mjg
Targeted Allele Detail

Summary

• Symbol: Tsc2^tm1.2Mjg
• Name: TSC complex subunit 2; targeted mutation 1.2, Michael J Gambello
• MGI ID: MGI:3712064
• Synonyms: Tsc2^ko
• Gene: Tsc2 Location: Chr17:24814790-24851604 bp, - strand Genetic Position: Chr17, 12.41 cM
• Alliance: Tsc2^tm1.2Mjg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:121748
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exons 1-4 were removed from the locus by crossing with mice expressing Cre recombinase in the germline. (J:121748)

Disease models

Expression

In Mice Carrying this Mutation:

6 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tsc2 Mutation: 78 strains or lines available

References

• Original: J:121748 Hernandez O, et al., Generation of a conditional disruption of the Tsc2 gene. Genesis. 2007 Feb;45(2):101-6
• All: 9 reference(s)