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Tcrbtm3.1Che
Targeted Allele Detail
Summary
Symbol: Tcrbtm3.1Che
Name: T cell receptor beta chain; targeted mutation 3.1, Jianzhu Chen
MGI ID: MGI:3712149
Synonyms: Vbeta(deltaneo)
Gene: Tcrb  Location: Chr6:40868230-41535305 bp, + strand  Genetic Position: Chr6, cytoband A-C
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:120387
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted
Mutation:    Insertion
 
Mutation detailsThe floxed pgk-neo was removed from the locus, leaving the Vbeta13 gene segment with its endogenous promoter and recombination signal sequences upstream of the D segment. (J:120387)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tcrb Mutation:  97 strains or lines available
References
Original:  J:120387 Sieh P, et al., Distinct control of the frequency and allelic exclusion of the V beta gene rearrangement at the TCR beta locus. J Immunol. 2001 Aug 15;167(4):2121-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory