Ube2n^{Gt(OST374154)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Ube2n^{Gt(OST374154)Lex}
• Name: ubiquitin-conjugating enzyme E2N; gene trap OST374154, Lexicon Genetics
• MGI ID: MGI:3712183
• Synonyms: Ubc13^-
• Gene: Ube2n Location: Chr10:95351024-95381520 bp, + strand Genetic Position: Chr10, 49.41 cM
• Alliance: Ube2n^{Gt(OST374154)Lex} page

Mutation origin

• Mutant Cell Line: OST374154
• Germline Transmission: Earliest citation of germline transmission: J:120846
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• A gene trap vector inserted into the first intron of the gene. (J:120846)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST374154	CG640752 ; (MGI Seq Detail)	3' RACE	multiple
  * GRCm39; (strand of gene trap mutagenesis)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ube2n Mutation: 21 strains or lines available

References

• Original: J:120846 Fukushima T, et al., Ubiquitin-conjugating enzyme Ubc13 is a critical component of TNF receptor-associated factor (TRAF)-mediated inflammatory responses. Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6371-6
• All: 3 reference(s)