Fcer1a^tm1Ftl
Targeted Allele Detail

Summary

• Symbol: Fcer1a^tm1Ftl
• Name: Fc receptor, IgE, high affinity I, alpha polypeptide; targeted mutation 1, Fu-Tong Liu
• MGI ID: MGI:3712201
• Synonyms: FcepsilonRIalpha
• Gene: Fcer1a Location: Chr1:173048851-173054781 bp, - strand Genetic Position: Chr1, 80.33 cM
• Alliance: Fcer1a^tm1Ftl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:120702
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• A neomycin resistance cassette was inserted into exon 3. (J:120702)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fcer1a Mutation: 23 strains or lines available

References

• Original: J:120702 Mayr SI, et al., IgE-dependent mast cell activation potentiates airway responses in murine asthma models. J Immunol. 2002 Aug 15;169(4):2061-8
• All: 1 reference(s)