Tg(Cyp19a1-cre)5909Gle
Transgene Detail

Summary

• Symbol: Tg(Cyp19a1-cre)5909Gle
• Name: transgene insertion 5909, Gustavo Leone
• MGI ID: MGI:3712299
• Transgene: Tg(Cyp19a1-cre)5909Gle Location: unknown
• Alliance: Tg(Cyp19a1-cre)5909Gle page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Cyp19a1-cre)5909Gle expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Cyp19a1

• Mutation details: This transgene uses the cytochrome P450, family 19, subfamily a, polypeptide 1 promoter to drive expression of cre recombinase in the placenta. The transgene also contains an IRES-luciferase, the rabbit beta-globin intron and the SV-40 polyA signal. X-gal staining revealed that cre was expressed strongly in the skin and lens as well as the trilaminate layers of the placenta. Almost a third of the fetuses (29%) expressed cre throughout internal organs, including the heart, liver and brain. (J:121714)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Cyp19a1 (species not specified) Summary of all recombinase alleles driven by Cyp19a1. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:121714 Wenzel PL, et al., Expression of Cre recombinase in early diploid trophoblast cells of the mouse placenta. Genesis. 2007 Mar;45(3):129-34
• All: 2 reference(s)