Ehd1^tm1Mhor
Targeted Allele Detail

Summary

• Symbol: Ehd1^tm1Mhor
• Name: EH-domain containing 1; targeted mutation 1, Mia Horowitz
• MGI ID: MGI:3712350
• Synonyms: Ehd1^-
• Gene: Ehd1 Location: Chr19:6326926-6350126 bp, + strand Genetic Position: Chr19, 4.4 cM
• Alliance: Ehd1^tm1Mhor page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:121819
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance cassette was inserted into exon 3 such that it fused to the first 164 bp of that exon and replaced exons 4 and 5. (J:121819)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ehd1 Mutation: 40 strains or lines available

References

• Original: J:121819 Rapaport D, et al., Recycling to the plasma membrane is delayed in EHD1 knockout mice. Traffic. 2006 Jan;7(1):52-60
• All: 2 reference(s)