Lbx2^tm1Fchn
Targeted Allele Detail

Summary

• Symbol: Lbx2^tm1Fchn
• Name: ladybird homeobox 2; targeted mutation 1, Fabian Chen
• MGI ID: MGI:3712795
• Synonyms: Lbx2^-
• Gene: Lbx2 Location: Chr6:83063348-83065224 bp, + strand Genetic Position: Chr6, 35.94 cM
• Alliance: Lbx2^tm1Fchn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:121890
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A targeting vector was designed to replace a portion of each exon 1 and 2 with a floxed PGK-neo cassette that was subsequently removed via cre mediated recombination. RT-PCR confirmed absence of transcript in mutants. (J:121890)

Expression

In Mice Carrying this Mutation:

98 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lbx2 Mutation: 11 strains or lines available

References

• Original: J:121890 Wei K, et al., Generation of mice deficient for Lbx2, a gene expressed in the urogenital system, nervous system, and Pax3 dependent tissues. Genesis. 2007 Jun;45(6):361-8
• All: 1 reference(s)