Plxnb1^tm1Rkun
Targeted Allele Detail

Summary

• Symbol: Plxnb1^tm1Rkun
• Name: plexin B1; targeted mutation 1, Rohini Kuner
• MGI ID: MGI:3713703
• Synonyms: Plxnb1^-
• Gene: Plxnb1 Location: Chr9:108924457-108948985 bp, + strand Genetic Position: Chr9, 59.63 cM
• Alliance: Plxnb1^tm1Rkun page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:121970
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Cre-mediated recombination was used to remove exons 12 through 17 creating a null allele. The absence of protein product was confirmed by western blot analysis. (J:121970)

Expression

In Mice Carrying this Mutation:	6 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Plxnb1 Mutation: 108 strains or lines available

References

• Original: J:121970 Deng S, et al., Plexin-B2, but not Plexin-B1, critically modulates neuronal migration and patterning of the developing nervous system in vivo. J Neurosci. 2007 Jun 6;27(23):6333-47
• All: 7 reference(s)