Plxnb2^tm1Rkun
Targeted Allele Detail

Summary

• Symbol: Plxnb2^tm1Rkun
• Name: plexin B2; targeted mutation 1, Rohini Kuner
• MGI ID: MGI:3713706
• Synonyms: Plxnb2^-
• Gene: Plxnb2 Location: Chr15:89039752-89064960 bp, - strand Genetic Position: Chr15, 44.68 cM, cytoband E3
• Alliance: Plxnb2^tm1Rkun page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:121970
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Cre-mediated recombination was used to removed exons 18 through 24 to create a null allele. The absence of transcript was confirmed by northern blot analysis. (J:121970)

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Plxnb2 Mutation: 88 strains or lines available

References

• Original: J:121970 Deng S, et al., Plexin-B2, but not Plexin-B1, critically modulates neuronal migration and patterning of the developing nervous system in vivo. J Neurosci. 2007 Jun 6;27(23):6333-47
• All: 4 reference(s)