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Trib3tm1Mws
Targeted Allele Detail
Summary
Symbol: Trib3tm1Mws
Name: tribbles pseudokinase 3; targeted mutation 1, Mark W Sleeman
MGI ID: MGI:3713755
Synonyms: Trib3-
Gene: Trib3  Location: Chr2:152179342-152185952 bp, - strand  Genetic Position: Chr2, 74.83 cM
Alliance: Trib3tm1Mws page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:122116
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe open reading frame was replaced with a LacZ-neo cassette to create a null allele. The absence of protein product was confirmed by western blot analysis. (J:122116)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Trib3 Mutation:  17 strains or lines available
References
Original:  J:122116 Okamoto H, et al., Genetic deletion of Trb3, the mammalian Drosophila tribbles homolog, displays normal hepatic insulin signaling and glucose homeostasis. Diabetes. 2007 May;56(5):1350-6
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory