Ffar1^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Ffar1^tm1Lex
• Name: free fatty acid receptor 1; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:3713759
• Synonyms: GPR40^-
• Gene: Ffar1 Location: Chr7:30559993-30560895 bp, - strand Genetic Position: Chr7, 19.25 cM
• Alliance: Ffar1^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:122092
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Exon 2 was replaced with a LacZ-neo cassette. (J:122092)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ffar1 Mutation: 18 strains or lines available

References

• Original: J:122092 Latour MG, et al., GPR40 is necessary but not sufficient for fatty acid stimulation of insulin secretion in vivo. Diabetes. 2007 Apr;56(4):1087-94
• All: 10 reference(s)