Tg(IghAb36-65)1Wys
Transgene Detail

Summary

• Symbol: Tg(IghAb36-65)1Wys
• Name: transgene insertion 1, Lawrence J Wysocki
• MGI ID: MGI:3713814
• Synonyms: Ars/A1
• Transgene: Tg(IghAb36-65)1Wys Location: unknown
• Alliance: Tg(IghAb36-65)1Wys page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(IghAb36-65)1Wys expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Igh (MGI:96442)

• Mutation details: The VH-D-JH exon from hybridoma clone #6-65 expressing an antibody to p-azophenylarsonate (Ars) was ligated to a linearized mu-delta cosmid construct. The transgene contains a natural promoter for the VH gene ant the natural mu-intron enhancer. (J:122260)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:122260 Benschop RJ, et al., Activation and anergy in bone marrow B cells of a novel immunoglobulin transgenic mouse that is both hapten specific and autoreactive. Immunity. 2001 Jan;14(1):33-43
• All: 12 reference(s)