Slc32a1^tm1Bros
Targeted Allele Detail

Summary

• Symbol: Slc32a1^tm1Bros
• Name: solute carrier family 32 (GABA vesicular transporter), member 1; targeted mutation 1, Nils Brose
• MGI ID: MGI:3714029
• Synonyms: Slc32a1^tm1Rhee, Viaat^-
• Gene: Slc32a1 Location: Chr2:158452687-158457668 bp, + strand Genetic Position: Chr2, 78.72 cM, cytoband H1-3
• Alliance: Slc32a1^tm1Bros page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:122318
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Coding exon 1 and part of intron 1 were replaced by a synaptobrevan 2-enhanced GFP minigene and a loxP flanked neo cassette. The syb2-EGFP fusion protein was not detected in mutants. (J:122318)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc32a1 Mutation: 55 strains or lines available

References

• Original: J:122318 Wojcik SM, et al., A shared vesicular carrier allows synaptic corelease of GABA and glycine. Neuron. 2006 May 18;50(4):575-87
• All: 1 reference(s)