C1galt1^tm1.2Rpmc
Targeted Allele Detail

Summary

• Symbol: C1galt1^tm1.2Rpmc
• Name: core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1; targeted mutation 2, Rodger P McEver
• MGI ID: MGI:3714051
• Synonyms: T-syn^-
• Gene: C1galt1 Location: Chr6:7845224-7872042 bp, + strand Genetic Position: Chr6, 3.37 cM, cytoband A1
• Alliance: C1galt1^tm1.2Rpmc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:122012
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exons 1 and 2 are deleted via cre-mediated recombination to form a null allele. (J:122012)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any C1galt1 Mutation: 26 strains or lines available

References

• Original: J:122012 Williams SA, et al., Fertilization in mouse does not require terminal galactose or N-acetylglucosamine on the zona pellucida glycans. J Cell Sci. 2007 Apr 15;120(Pt 8):1341-9
• All: 7 reference(s)