Cul3^tm1Jdsr
Targeted Allele Detail

Summary

• Symbol: Cul3^tm1Jdsr
• Name: cullin 3; targeted mutation 1, Jeffrey D Singer
• MGI ID: MGI:3714267
• Synonyms: Cul3^flox
• Gene: Cul3 Location: Chr1:80242640-80318197 bp, - strand Genetic Position: Chr1, 41.24 cM, cytoband C4
• Alliance: Cul3^tm1Jdsr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:122228
• Parent Cell Line: AK7 (ES Cell)
• Strain of Origin: 129S4/SvJaeSor

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exons 4-7 were flanked with loxP sites. An FRT-flanked neo was included in intron 3. (J:122228)

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cul3 Mutation: 51 strains or lines available

References

• Original: J:122228 McEvoy JD, et al., Constitutive turnover of cyclin E by Cul3 maintains quiescence. Mol Cell Biol. 2007 May;27(10):3651-66
• All: 10 reference(s)