Ebf2^{tm2.1(Zfp423)Reed}
Targeted Allele Detail

Summary

• Symbol: Ebf2^{tm2.1(Zfp423)Reed}
• Name: early B cell factor 2; targeted mutation 2.1, Randall R Reed
• MGI ID: MGI:3714342
• Synonyms: O/E3^OAZ
• Gene: Ebf2 Location: Chr14:67470741-67668367 bp, + strand Genetic Position: Chr14, 34.63 cM, cytoband D-E1
• Alliance: Ebf2^{tm2.1(Zfp423)Reed} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:122275
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted
• Mutation: Insertion
• Mutation details: The floxed neo was removed from the locus via cre mediated recombination, leaving the full length cDNA for zing finger protein 423, followed by IRES-3NLS-YFP-pA in place of the first five exons of the locus. (J:122275)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ebf2 Mutation: 30 strains or lines available

References

• Original: J:122275 Cheng LE, et al., Zfp423/OAZ participates in a developmental switch during olfactory neurogenesis. Neuron. 2007 May 24;54(4):547-57
• All: 2 reference(s)