Tg(Scg2-tTA)1Jt
Transgene Detail

Summary

• Symbol: Tg(Scg2-tTA)1Jt
• Name: transgene insertion 1, Joseph S Takahashi
• MGI ID: MGI:3714754
• Synonyms: Scg2::tTA
• Transgene: Tg(Scg2-tTA)1Jt Location: unknown
• Alliance: Tg(Scg2-tTA)1Jt page

Transgene origin

• Strain of Origin: CD-1

Transgene description

• Transgene Type: Transgenic (Transactivator)
• Mutation: Insertion
• Mutation details: 9.85 kb of DNA upstream from the mouse Scg2 translational start site was placed upstream of the tTA gene encoded in the pMMY20 plasmid. The transgene shows expression in the brain and is enriched in the suprachiasmatic nucleus. (J:116189)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:116189 McDearmon EL, et al., Dissecting the functions of the mammalian clock protein BMAL1 by tissue-specific rescue in mice. Science. 2006 Nov 24;314(5803):1304-8
• All: 12 reference(s)