Tg(tetO-Arntl)1Jt
Transgene Detail

Summary

• Symbol: Tg(tetO-Arntl)1Jt
• Name: transgene insertion 1, Joseph S Takahashi
• MGI ID: MGI:3714756
• Synonyms: tetO::Bmal1-HA
• Transgene: Tg(tetO-Arntl)1Jt Location: unknown
• Alliance: Tg(tetO-Arntl)1Jt page

Transgene origin

• Strain of Origin: CD-1

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(tetO-Arntl)1Jt expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Bmal1 (MGI:1096381)

• Mutation details: A 2.1 kb fragment containing hemagglutinin (HA)-tagged Arnt1 cDNA was inserted into a vector downstream of the tetracycline operator (tetO) sequence. The construct was injected into fertilized CD-1 oocytes. (J:116189)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:116189 McDearmon EL, et al., Dissecting the functions of the mammalian clock protein BMAL1 by tissue-specific rescue in mice. Science. 2006 Nov 24;314(5803):1304-8
• All: 2 reference(s)