Map2k1^tm1Chrn
Targeted Allele Detail

Summary

• Symbol: Map2k1^tm1Chrn
• Name: mitogen-activated protein kinase kinase 1; targeted mutation 1, Jean Charron
• MGI ID: MGI:3714918
• Synonyms: Map2k1^floxed, Mek1^fl
• Gene: Map2k1 Location: Chr9:64093066-64160887 bp, - strand Genetic Position: Chr9, 34.55 cM
• Alliance: Map2k1^tm1Chrn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:112223
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 3 is floxed and can be removed by Cre recombination to create a null allele. (J:112223)

Expression

In Mice Carrying this Mutation:

5 RNA-Seq or microarray experiment(s)

Tumor Data

List all tumor models in MMHCdb carrying Map2k1^tm1Chrn

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Map2k1 Mutation: 94 strains or lines available

References

• Original: J:112223 Bissonauth V, et al., Requirement for Map2k1 (Mek1) in extra-embryonic ectoderm during placentogenesis. Development. 2006 Sep;133(17):3429-40
• All: 34 reference(s)