Epb41l5^Gt(XC282)Byg
Gene trapped Allele Detail

Summary

• Symbol: Epb41l5^Gt(XC282)Byg
• Name: erythrocyte membrane protein band 4.1 like 5; gene trap XC282, BayGenomics
• MGI ID: MGI:3714922
• Synonyms: Ebp4.1l5^GT2
• Gene: Epb41l5 Location: Chr1:119472767-119576730 bp, - strand Genetic Position: Chr1, 52.32 cM
• Alliance: Epb41l5^Gt(XC282)Byg page

Mutation origin

• Mutant Cell Line: XC282
• Germline Transmission: Earliest citation of germline transmission: J:122548
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT1Lxf Vector Type: gene trap
• Mutation details: The beta-galactosidase gene was fused after the first 392 amino acids, which includes the complete FERM domain. (J:122548)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  XC282	CC178219 ; (MGI Seq Detail)	5' RACE	Chr1:119535718-119545306 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  17 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Mice Carrying this Mutation:	1 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Epb41l5 Mutation: 46 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:122548 Lee JD, et al., The FERM protein Epb4.1l5 is required for organization of the neural plate and for the epithelial-mesenchymal transition at the primitive streak of the mouse embryo. Development. 2007 Jun;134(11):2007-16
• All: 3 reference(s)