Itgb1^tm4Ref
Targeted Allele Detail

Summary

• Symbol: Itgb1^tm4Ref
• Name: integrin beta 1 (fibronectin receptor beta); targeted mutation 4, Reinhard Fassler
• MGI ID: MGI:3714996
• Synonyms: Beta1EII
• Gene: Itgb1 Location: Chr8:129412135-129459681 bp, + strand Genetic Position: Chr8, 76.09 cM, cytoband E2
• Alliance: Itgb1^tm4Ref page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:122649
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• LoxP-flanked allele without the beta-galactosidase reporter gene. (J:122649)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Itgb1 Mutation: 60 strains or lines available

References

• Original: J:122649 Kren A, et al., Increased tumor cell dissemination and cellular senescence in the absence of beta(1)-integrin function. EMBO J. 2007 Jun 20;26(12):2832-42
• All: 1 reference(s)