Pdgfrb^tm1Mdt
Targeted Allele Detail

Summary

• Symbol: Pdgfrb^tm1Mdt
• Name: platelet derived growth factor receptor, beta polypeptide; targeted mutation 1, Michelle D Tallquist
• MGI ID: MGI:3715030
• Synonyms: PDGFRbeta^fl
• Gene: Pdgfrb Location: Chr18:61178222-61218133 bp, + strand Genetic Position: Chr18, 34.41 cM
• Alliance: Pdgfrb^tm1Mdt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:122584
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Intragenic deletion
• Exons 1 to 6 are floxed. Cre recombination removed exons 1 to 6 creating a null allele. (J:122584)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pdgfrb Mutation: 87 strains or lines available

References

• Original: J:122584 Richarte AM, et al., Cooperation between the PDGF receptors in cardiac neural crest cell migration. Dev Biol. 2007 Jun 15;306(2):785-96
• All: 6 reference(s)