Shisa4^tm1Sia
Targeted Allele Detail

Summary

• Symbol: Shisa4^tm1Sia
• Name: shisa family member 4; targeted mutation 1, Shinichi Aizawa
• MGI ID: MGI:3715224
• Synonyms: mShisa4^lacZ
• Gene: Shisa4 Location: Chr1:135298795-135302975 bp, - strand Genetic Position: Chr1, 58.58 cM
• Alliance: Shisa4^tm1Sia page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:122557
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: 49bp upstream of the initiation site and the following intron were replaced with a lacZ/neo cassette creating a null allele. Insertion was confirmed by a beta-galactosidase assay. (J:122557)

Expression

In Mice Carrying this Mutation:

2 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Shisa4 Mutation: 15 strains or lines available

References

• Original: J:122557 Furushima K, et al., Mouse homologues of Shisa antagonistic to Wnt and Fgf signalings. Dev Biol. 2007 Jun 15;306(2):480-92
• All: 1 reference(s)