Oc90^tm1Ywl
Targeted Allele Detail

Summary

• Symbol: Oc90^tm1Ywl
• Name: otoconin 90; targeted mutation 1, Yunxia Wang Lundberg
• MGI ID: MGI:3715290
• Gene: Oc90 Location: Chr15:65747902-65784246 bp, - strand Genetic Position: Chr15, 29.16 cM
• Alliance: Oc90^tm1Ywl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:122533
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 3 through 14 were replaced with a neo cassette. The absence of transcript was confirmed using semiquantitative RT-PCR. (J:122533)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Oc90 Mutation: 26 strains or lines available

References

• Original: J:122533 Zhao X, et al., Gene targeting reveals the role of Oc90 as the essential organizer of the otoconial organic matrix. Dev Biol. 2007 Apr 15;304(2):508-24
• All: 4 reference(s)